* Corresponding/co-corresponding author
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Selected Publications
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12. Mao X*, Gu H, Kim D, Kimura Y, Wang N, Xu E, Kumbhar R, Ming X, Wang H, Chen C, Zhang S, Jia C, Liu Y, Bian H, Karuppagounder SS, Akkentli F, Chen Q, Jia L, Hwang H, Lee SH, Ke X, Chang M, Li A, Yang J, Rastegar C, Sriparna M, Ge P, Brahmachari S, Kim S, Zhang S, Shimoda Y, Saar M, Liu H, Kweon SH, Ying M, Workman CJ, Vignali DAA, Muller UC, Liu C, Ko HS*, Dawson VL*, Dawson TM*. Aplp1 interacts with Lag3 to facilitate transmission of pathological α-synuclein. Nature Communications, 2024 May 31;15(1):4663. doi: 10.1038/s41467-024-49016-3. PDF and SI
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11. Chen C, Kumbhar R, Wang H, Yang X, Gadhave K, Rastegar C, Kimura Y, Behensky A, Kotha S, Kuo G, Katakam S, Jeong D, Wang L, Wang A, Chen R, Zhang S, Jin L, Workman CJ, Vignali DAA, Pletinkova O, Jia H, Peng W, Nauen DW, Wong PC, Redding-Ochoa J, Troncoso JC, Ying M, Dawson VL, Dawson TM, Mao X*. Pathological Tau transmission initiated by binding lymphocyte-activation gene 3. Advanced Science. 2024, Feb 7:e2303775. (Back Cover of the issue). PDF and SI
10. Choi CY, Gadhave K, Villano J, Pekosz A, Mao X*, Jia H*. Generation and characterization of a humanized ACE2 mouse model to study long-term impacts of SARS-CoV-2 infection. Journal of Medical Virology. 2024; 96:e29349. PDF and SI
9. Cheng FY, Kotha S, Fu M, He WW*, Mao X*. Nanozyme enabled protective therapy for neurological diseases. Invited Review. Nano Today, 2024, 54, 102142. (Review) PDF
8. Butler YR, Liu YQ, Kumbhar R, Zhao PR, Gadhave K, Wang N, Li YM, Mao X*, Wang WJ*. Fibril-specific nanobody prevents prion-like α-synuclein spreading. Nature Communications. 2022, 13:4060.​ PDF
7. Zhang SN, Liu YQ, Jia CY, Lim YJ (co-first), Feng GQ, Xu EQ, Kimura Y, Long HF, Tao YQ, Zhao CY, Wang CC, Liu ZY, Hu JJ, Ma MR, Liu ZJ, Jiang L, Li D, Wang RX, Dawson VL, Dawson TM*, Li YM*, Mao X*, Liu C*. Mechanistic basis for receptor-mediated pathological α-synuclein fibril cell-to-cell transmission in Parkinson's disease. Proc Natl Acad Sci. USA. 2021;118(26): e2011196118. PDF
6. Liu YQ, Mao YY (co-first), Xu EQ, Jia HM, Zhang S, Dawson VL, Dawson TM, Li YM*, Zheng Z*, He WW*, Mao X*. Nanozyme Scavenging ROS for Prevention of Pathologic α-Synuclein Transmission in Parkinson’s Disease. Nano Today. 2021, 36, 101027. PDF
5. Kam TI#, Mao X#, Park HJ# (# equal contribution), Chou SC, Karuppagounder SS, Umanah GE, Yun SP, Brahmachari S, Panicker N, Chen R, Andrabi SA, Qi C, Poirier GG, Pletnikova O, Troncoso JC, Bekris LM, Leverenz JB, Pantelyat A, Ko HS, Rosenthal LS, Dawson TM and Dawson VL. Poly (ADP-ribose) Drives Pathologic α-Synuclein Neurodegeneration in Parkinson’s Disease. Science. 2018;362(6414). pii: eaat8407. PDF
4. Mao X, Ou MTH, Karuppagounder SS, Kam TI, Yin XL, Xiong YL, Ge P, Umanah GE, Brahmachari S, Shin JH, Kang HC, Zhang JM, Xu JC, Chen R, Park HJ, Andrabi SA, Kang SU, Gonçalves RA, Liang Y, Zhang S, Qi C, Lam S, Keiler JA, Tyson J, Kim DH, Panicker N, Yun SP, Workman CJ, Vignali DAA, Dawson VL, Ko HS, Dawson TM. Pathological α-synuclein transmission initiated by binding lymphocyte-activation gene 3, Science. 2016;353(6307). pii: aah3374. PDF
3. Zhang M#, Mao X# (# equal contribution), Wang CX, Zeng WF, Zhang CL, Li ZJ, Fang Y, Yang YL, Liang W, Wang C. The effect of graphene oxide on conformation change, aggregation and cytotoxicity of HIV-1 regulatory protein (Vpr). Biomaterials. 2013;34(4):1383-90. PDF
2. Mao X, Guo YY, Luo Y, Niu L, Liu L, Ma XJ, Wang HB, Yang YL, Wei GH, Wang C. Sequence effects on peptide assembly characteristics observed by using scanning tunneling microscopy. J. Am. Chem. Soc. 2013;135(6):2181-7. PDF
1. Mao X#, Wang CX# (# equal contribution), Wu XK, Ma XJ, Liu L, Zhang L, Niu L, Guo YY, Li DH, Yang YL, Wang C. Beta structure motifs of islet amyloid polypeptides identified through surface-mediated assemblies. Proc. Natl. Acad. Sci. U.S.A. 2011;108(49):19605-10. PDF